The End of Aging?

Cutting edge research in cellular genetics is showing us that aging is not normal or inevitable.  In fact, the top research labs are showing us that Aging is a disease that can be prevented, slowed, and potentially even reversed.

Most of us are going to live longer than we think. Are we going to live better – enjoying high level energy, fitness, and a happy brain throughout our lifespan?

Is there any point in keeping our bodies alive if our brain is failing & we FEEL decrepit & even older than our age?

Is suffering with decay, degeneration, inflammation, pain, fatigue, and depression really living? Is it inevitable? This “accelerated aging & decay” is the root problem.

Extending our health span – so we enjoy high level energy and youthful vitality to the very end of our lifespan is the most important. Imagine, no chronic disease, no need for drugs, no doctor visits for disease problems, no suffering in a nursing home.

It is also about staying healthy to beyond age 100 or beyond age 120 and living our passion and making a difference in the world – right up to the end of our lifespan.

Summary:

  • Aging is not inevitable – it can be prevented and even reversed
  • The DNA blueprint to be young is always present – even when we are old
  • Most of feeling “old” is not from DNA damage (our computer hard-drive) but from epigenetic problems (our software)
  • We have a software backup of youth – even when we are old
  • We activate this epigenetic software of youth through:
    • Intermittent fasting – this can be done easily with ketogenic fasting
    • High Intensity Interval Training – just 15 minutes 2X/week can do the job – especially when combined with Intermittent fasting.
    • Low Level Laser Therapy – the kind of lasers we use at Renovare have been shown to directly boost NAD+ and indirectly boost this anti-aging pathway as well.
    • Temperature challenges – get warm as in a sauna or summer in Arizona and then get cool as in a cold/cool shower or immersion in an unheated pool in the winter
    •  Specific nutraceuticals:
      • Methylated Resveratrol – Resveratin Plus is what I use.
      • Nicotinomide Mononucleotide (NMN) – a NAD+ precursor – needs to be liposomal and combined with trimethylglycine to be most effective.  NAD+ Gold from Quicksilver Scientific is best.
      • Time released Alpha Lipoic Acid. ALA Max is what I use.
      • Berberine, Burdock Root, Curcumin, Tumeric, and Quercitin.
    • Great sleep and stress management – Our Peaceful Brain Training Class is a fun, easy way to learn the tools that work best for you

Too much comfort, too much artificial, nutrient-deprived processed food, too little physical challenge, too much stress, too much sitting in the easy chair ACCELERATES our aging.   We need some discomfort & challenge to stay youthful.

COMFORT KILLS

What if chronic pain, excessive inflammation, diabetes, heart disease, Alzheimer’s, cancer, osteoporosis, and arthritis are just SYMPTOMS of accelerated aging & decay?  What would happen if be changed our focus to ending this plague of accelerated aging & decay?

The good news is that research with identical twins shows us that only 20% of our aging and health-span is genetic.  The rest is our lifestyle choices and is in our hands.

Dr. David Sinclair, Ph.D is a molecular geneticist, professor at Harvard,  and leading researcher in aging.  His research delves into why we age – the underlying cell mechanisms behind aging. In his excellent book, “Lifespan – Why we Age and What We Can Do About It” explains that aging is not caused by problems with our DNA.  Rather, aging results from breakdown in our epigenetic cell repair programs for DNA.

Our genes containing the blueprints to make every protein & body part are the Hardware of our computer.  Our epigenetics is the software.  Without our software (epigenetics) working properly, our computer is just a heavy piece of frustrating junk.

Like our personal computer, our genetics (DNA) is the hard drive that stores the information and programs.  Our epigenetics is our software that includes DNA repair programs.  Much like hard drive disc repair programs, our epigenetic software must keep up with repairs or our software becomes corrupted and our computer “ages” and slips towards “dis­-ease”.

In our cells, some DNA damage is inevitable and normal. This is not the cause of aging.  We have complex DNA repair pathways called “epigenetics” that quickly and efficiently repair our DNA damage when working properly. Failure of these epigenetic “software” programs to keep up with needed “hardware” repairs leads to decay and aging.

You can also think of DNA like a beautiful Steinway Grand Piano.   Our Epigenetics is the pianist – the piano player that determines & plays the songs as well as repairing & tuning our piano so we enjoy music (Wellness) rather than the noise, decay, decline, & disease of Aging. We need a skilled and healthy pianist to enjoy the music of Wellness for Life.

Dr. David Sinclair’s research-supported Information Theory of Aging describes aging as a breakdown of our epigenetic software triggered by lifestyle choices that fail to fit our unique needs.  This leads to so much DNA damage that our software fails to keep up and our cells breakdown leading to the damage, inflammation, & decay that we call Aging. This is neither normal nor inevitable.

Dr. Sinclair’s lab has shown that there is a backup copy of youth in our cells. In mice, his lab has reset the youthful copy to reverse aging. With cloning, using a cell from an older animal results in a youthful “baby”, not an old baby for this reason.

We have 3 genes on the body that reverse our aging when we turn them on.  Jelly fish do this all the time so they don’t age.  We are learning to do this in mice, dogs, and even humans.

Three of the major age reversing genes that we all share are called Sirtuins, mTOR, and AMPK.  These 3 genes are critical to maintain our youthful, healthy software(epigenome):

Sirtuins

  • Especially effective at maintaining our youthful epigenomic software
  • Activated by methylated resveratrol (pterostilbene) concentrates
  • Activated by Nicotinomide Mononucleotide (NMN) – professional-grade supplements that are liposomal formulations combined with trimethylglycine appear the most effective.  The formulation I trust and take personally is Quicksilver Scientific’s NAD+ Gold.  NAD decline underlies accelerated aging and inflammation.  Boosting NAD levels with NMN is key to support:
    • Improved mitochondrial function
    • Youthful metabolism
    • High level stamina and youthful vigor
    • Cellular repair and protection
    • Improved Brain health: youthful memory, focus, and concentration

Harvard researchers have found that injecting NMN into old mice for just one week resulted in their mitochondria becoming like those of young mice.  In fact, when NMN was first give to old mice, they broke the treadmill!  The lab staff called it the “Great Mouse Treatmill Failure of 2017” when the old mice exceeded the tracking program limit of 3 kilometers – no mouse of any age had ever exceeded this before! Imagine being able to run an ultra-marathon as a senior citizen.

We can also activate our age-reversing Sirtuin gene with:

  • Low level Laser therapy (LLLT) or healing cold lasers like our Erchonia PL-T, FX 405, or EVRL lasers. 

The graphic below shows how the LLLT stimulus activates receptors leading to elevated sirtuin (Sirt1) activating the anti-aging effects of making brand new mitochondria (mitochondrial biogenesis), apoptosis (getting rid of decrepit old cells that create disease), and cell protecting anti-oxidant effects.

Intermittent fasting: I use green tea, MCT oil, and Collagen protein in my breakfast drink on my workout days.  It increases my strength up to 20%.  This carb fasting approach triggers ketosis so I am burning fat for fuel which is much more efficient than burning sugar leading to increased muscle strength & efficiency.

  • High intensity interval training – I combine intermittent keto fasting with my NOW-T exercise sessions 2X/week with Austin in our clinic.  It takes just 15 minutes of variable resistance training 2X/week to powerfully activate the anti-aging pathways while boosting mitochondrial wellness.

The mTOR/mTORC1 gene pathway (shown above) integrates the signals between food availability and cell growth.

Food available = cell growth. Too much food available = too much growth leading to:

  • Cancer
  • Atherosclerotic heart disease
  • Stroke
  • Dementia – esp. Alzheimer’s type
  • Obesity
  • Polycystic ovarian disease
  • Insulin resistance and most of the chronic diseases of decay and aging.

No food available = stop growing and start repairing.  We NEED a break from food.  Intermittent fasting is a simple, painless way to activate this critical anti-aging signaling.

Inhibiting mTOR turns on the “stop growing and start repairing” switch.  Nutrients that also do this include:

  • Resveratrol
  • Quercitin
  • Turmeric

To learn more: https://thefastingmethod.com/fasting-and-autophagy-mtor-autophagy-1/

AMPK is our master switch for metabolism.  It is our “Fat Switch” – when turned on we burn fat for fuel, when turned off we store fat. Critical AMPK activating nutrients include: resveratrol, Alpha Lipoic Acid, Berberine, Burdock Root, Rose Hips, Short Chain Fatty Acids (SCFA’s are made from fiber by a healthy microbiome).  Exercise esp. high intensity interval training and fasting also activate this critical youth promoting pathway.  My favorite supplements to turn on our AMPK “Fat burning” switch are Glycoberine MX and ALA Max (time released high potency Alpha Lipoic Acid)

For the first time in the history of the world, we have more people over age 65 than children under the age of 5. What are we going to do with an ever-aging population that is decaying with an ever-growing list of chronic diseases headed towards a nursing home?  We are facing the bankruptcy of not only our health care systems but our entire economy.  This is in addition to the massive pain and suffering of those decaying through excessive inflammation, exhaustion, depression, and dementia. We MUST reverse the terrible decay & aging that plagues our aging population.

Mitochondria: The Key to Everything

Wellness = Energy, Energy, Energy!!!

Cell mitochondria anatomy. 3d illustration

Our energy comes from our mitochondria which are tiny energy factories packed into our cells – we have 2000 mitochondria packed into the tiny cells of each heart and brain cell.

How well our cell energy factories (mitochondria) generate ATP (the fuel that powers us) determines our biologic age.

We can’t change our chronological age (number of birthdays) unless we lie (not that
anyone we know would ever do that) 🙂

We can change our biologic age – the age we function. We all know people who are age 50 but look and feel age 80 as well as people age 80 who look and feel age 50. My Dad is a great example of the latter.

A key part of aging is losing many of our precious mitochondria. To make matters worse,
our remaining mitochondria suffer damage leading to an energy deficit. Remember,
 Wellness is energy, energy, energy. To sum it up:

Energy =

  • number of mitochondria in each cell
  • Health & efficiency of those mitochondria

We are as Young as Our Mitochondria!

What can we do to support our mitochondria?

  1. We can improve the Well ness & functional efficiency of the mitochondria we
    have.
  2. We can make new mitochondria (biogenesis) – at any age!

Improving the Efficiency of Our Mitochondria

If we are not making energy efficiently, we are instead making fat & destructive free
radicals. Here are some steps that are proven to work:

  1. 635 nm wavelength red coherent laser therapy. The Erchonia professional grade
    cold lasers (do not generate harmful heating) are the most effective available
    anywhere to do this – with the research to back it up. These healing lasers boost
    energy production by our mitochondria between 40 and 50%. An amazing “battery
    charge”. This laser photonic energy also triggers multiple anti-aging cellular
    pathways. The violet and red laser combination we use also trigger making new
    mitochondria.
  2. Eat nutrient dense whole foods and avoid processed foods.
  3. Avoid the nasty mitochondrial poison, glyphosate (Roundup), which is sprayed on
    our crops and concentrated in our vegetables, meats, and processed food. Eating
    organic is phenomenally important to minimize exposure. The average American
    has 1 pound of this toxin in their body – no wonder we are so fat, sick, tired,
    anxious, depressed, and inflamed.
  4. Eat less sugar and fruit – high levels are toxic to our mitochondria and metabolism.
  5. Eat more Veggies, quality protein, and healthy fats: Olive, Coconut, Avocado, MCT
    oil are good sources.
  6. Supplement smart – the Core 4:
    • A high-grade Multiple Vitamin/Mineral like Mega Multi Pro
    • A bioavailable source of high potency magnesium like Acti-mag
    • Vitamin K2-D3 at optimal dose based on blood lab testing
    • A high quality, clean, bioavailable Omega 3 like Omega Pure 1300 Pro which
      is 320% better absorbed than regular fish oil.

7. Advanced Supplementation:

  • A probiotic like MegaSpore Biotic to support our Microbiome – the 100
    TRILLION bacteria/microbes that live mostly in our gut. Did you know that
    our Microbiome talks to our Mitochondria? We MUST have a healthy,
    diverse, balanced Microbiome for our Mitochondria to work well.
  • Time-released Alpha Lipoic Acid. I use ALA-Max which we have found to be
    the most effective form.
  • A bioactive high-grade methylated resveratrol. I take our Resveratin Plus (Resveratrol/Pterostilbene Complex) to activate the Sirtuin pathways to turn off the aging cell signaling pathways.
  • Coenzyme Ql0 I CoQl0 I ubiquinone – we especially like the more active Ubiquinone form.
  • Pyrroloquinoline Quinone I PQQ I Methoxatin
  • L-carnitine
  • Creatine

8. Intermittent fasting: I use green tea, MCT oil, and Collagen protein in my breakfast drink on my workout days. It increases my strength up to 20%. This carb fasting approach triggers ketosis so I am burning fat for fuel which is much more efficient than burning sugar leading to my increased muscle strength & efficiency.

9. High intensity interval training – I combine fasting with my NOW-T exercise
sessions 2X/week with Austin in our clinic. It takes just 15 minutes of variable
resistance training 2X/week to powerfully activate the anti-aging pathways while
boosting mitochondrial wellness.

10. Exposure to cold. I use cold (cool in the summer here) showers and cold
immersions in our unheated swimming pool in the winter.

11. Great quality and quantity of deep, restful sleep is profoundly important for our
mitochondrial health and wellness.

12. Effective relaxation techniques – especially meditation

13. Get enough Sunlight while avoiding sunburns – we are “solar powered”.

Making New Mitochondria

This is called mitochondrial biogenesis and can be turned on at any age. Most of
what works to improve the efficiency of our Mitochondria also works to trigger
biogenesis. Here are the top triggers for making new mitochondria:

  • Intermittent fasting
  • High intensity interval training – I combine fasting with my NOW-T sessions
    2X/week with Austin in our clinic. Takes just 15 minutes of variable
    resistance training 2X/week to powerfully activate the anti-aging pathways
    while boosting mitochondrial wellness.
  • Supplement with bioactive methylated Resveratrol (pterostilbene)

Prologel Pain Relief Therapy

Much common muscle and joint pain is actually Neuropathic pain. This means superficial nerves just under the skin become compressed by tight muscles, fascial adhesions (scar tissue), overuse, and trauma triggering inflammation of the shallow nerves. Our nerves are sensitive since the Nervi Nervorum innervates the surface of the nerve and senses compression and irritation. This nerve irritation and swelling can then trigger:

  • Neurogenic inflammation = irritated nerve triggers inflammation of tissues around it creating vasodilation(swelling), a red flare response, heat, and pain.
  • Inflammation of nerve endings in area controlled by the nerve.
  • Irritation of spinal cord
  • Chronic pain cycles in brain and spinal cord
  • Limbic system activation which triggers fight or flight toxic stress response upsetting our critical autonomic control system causing’
    • Anxiety and loss of peaceful calm
    • Turn off our healing and repair response
    • Poor digestion and detoxification
    • Allergy and autoimmune problems a Excessive inflammation
    • Exaggerated and persistent pain

These areas of surface nerve neurogenic inflammation can feel like trigger points, active acupuncture points, and tender, ropy, tight tissue areas.

We can treat these with negative pressure, gentle positive pressure, prologel, and therapeutic healing lasers. Effective treatment creates at least 50% pain relief in just minutes. Long-term relief involves solving the puzzle of why you suffer with chronic pain. Junk food, gluten, diet sodas, poor sleep, high stress, poor muscle tone, low Vitamin D, low electrolytes, and high EMF exposures are just a few triggers of chronic pain

Effective treatment of Neurogenic inflammation of superficial sensors nerves can be a game changer. We have 13 types of pain receptors. Until now, the critical ASIC receptors have been ignored. Prologel is formulated to turn off this critical ASIC pain as well as the TRPA and TRPV receptors. Rubbing Prologel into your pain producing areas each AM & PM or more often as home care works with our in-office treatment and laser therapies for home care.

These 2 products are available for sale in our clinic:

Original PAIN RELIEF formula will turn off the ASIC, TRPA, TRPV pain

PAIN RELIEF formula plus 1000 mg Broad spectrum CBD high concentration with extra effectiveness for the TRPV pain receptor. Good for cold weather change pain relief.

Call US Today to Order this product at 623-776-0206

Exciting NEWS!! Renovare Brain Wellness Introduces the NEW Erchonia FX 405 FDA Approved Laser

FDA APPROVED TO TREAT LOW BACK PAIN, PLANTAR FASCITIS, AND CHRONIC PAIN ANYWHERE

Some of the Researched Mechanisms of Action from over 10,000 published research papers (the most researched of our therapies):

  • Reduce inflammation in brain and body
  • Increase mitochondrial energy production 40 – 50% – a battery charger for your brain and body to power healing and Wellness!
  • Increases blood flow to the brain
  • Repair Leaky Gut and Leaky Brain – and prevent further damage
  • Stimulates making new mitochondria (biogenesis) and new nerve cells in the brain – even stimulates new brain stem cells
  • Protects and even reverses Amyloid Plaques and Neurofibrillary tangles associated with dementia
  • Boosts mental clarity & high level focus, concentration, and memory
  • Enhances our mental sense of well-being and peaceful brain balance
  • Boosts immune response to protect against infections in the brain & body and even directly kill pathogens
  • Promotes anti-oxidant systems to protect us against destructive free-radicals and accelerated aging
  • Protects against brain cell death from excitotoxicity and injury
  • Research shows it can protect against stroke and heart attack
  • Increases muscle strength and protects from injury
  • Accelerates bone healing and repair
  • Decreases stress hormones & boosts youth-promoting Human Growth Hormone
  • Cumulative benefits so continue to improve after the therapy sessions are completed.
  • No FDA reported side effects from research studies – safe & effective
  • Opioid drug alternative effective for chronic back, hip, and knee pain.
  • Increase Vagal nerve & parasympathetic activity to promote:
    • Peaceful brain free of anxiety and depression symptoms
    • Better sleep, digestion, and detoxification
    • Healing & repair
    • Immune tolerance (helps with food reactions and autoimmune problems)

Come Visit us on June 11, 2021 for our OPEN HOUSE to introduce the FX 405, Gift certificates for everyone who attends, healthy snacks, and much more.

CALL RENOVARE to RSVP at 623-776-0206. You can chose from 3 event times 4pm, 5 pm or 6pm. We look forward to seeing you!

Role of Our Microbiome in Staying Well With Viral Infections

The Microbiome is currently one of the most intensely researched areas in science. PubMed, the NIH federal library of medical research, shows over 86,000 results for published research papers on our Microbiome, almost all of it in the last five years. 

What is our Microbiome?

What are practical steps to support our microbiome and our immune system so we can stay well in challenging times:

It is the 100 Trillion non-human cells that live in us and on us.  It is the “germs” that live on our skin (2 million per ½ inch square on our forearm), in our mouth, our sinuses, our bloodstream, our gut and everywhere inside and outside our body.  In fact, our human cells are outnumbered by the “germs” that make up our Microbiome.  In reality,  we are 100 Trillion “germs” covered in human skin.

Most of these “germs” are bacteria and viruses that seek to coexist peacefully with us and promote our health and wellbeing. Most of them live in our gut, especially in our Large Intestine.  They play critical roles in digestion, metabolism, immune health, brain health, and store 98% of all the genetic information (DNA) we need to stay healthy and thrive.  In fact, our mitochondria talk to our gut bacteria.  We need a healthy microbiome to have healthy mitochondria, the foundation of energy and Wellness!

Staying Well In  Covid

If our immune system can handle 100 trillion germs in and on us, can it also handle the common cold, flu, or Covid virus?  Of course – as long as we take care of our immune system so it is working reasonably well.  What would happen if we put as much time, effort, and energy into boosting our Microbiome and immune Wellness as we do to masking, distancing, and worrying?

  1. The less your food has been doctored, the less you need a doctor. Minimize eating food that has been processed or doctored.  Go light on dead food that comes from “food coffins” –  the boxes, cans, and plastic that entombs dead food.  Eat more of the “fresh stuff”.
  2. Eat what your body likes rather than what you like.  We tend to like the sugary “junk food” loaded with excitotoxic taste enhancers that excite our brain neurons to death.  They also starve our microbiome “rainforest” of the critical fiber it depends on.  A piece of cake feeds only us and makes us old, fat, and sick.  A piece of broccoli feeds both our body and our microbiome to keep us lean, energized, and youthful.
  3. Fix your metabolism.  When is works, you have a “thin person” microbiome. When it is in trouble, we often develop a “fat person” microbiome.  Fixing your metabolism often requires a “solve the puzzle” approach involving optimizing our mitochondria, gut health, brain balance, eating smart & supplementing to fit our unique genetic needs, optimize sleep, and detox.  Get guidance from experienced professionals like we have at Renovare if you need help in this area.
  4. Feed Your Microbiome Diversity.  Repairing our microbiome diversity is critical to restoring Wellness. An important indicator of a healthy microbiome is Great bowel movements.  This means at least 2/day, formed dark brown, don’t float, no straining, and almost no need to toilet tissue to clean after.  Here are the practical steps:
  5. Eat the Rainbow.  Strive to eat 9 colors or fresh/frozen veggies or fruits per day.  Always go heavy on veggies and much lighter on fruit.
  6. Each day, eat one of the Root Veggies, eat two of the prebiotic foods, and at least one forkful of a fermented food from the lists below
Root VeggiesPrebiotic FoodsFermented Food with Live culture (in refrigerator section)
Turnips          Dandelion GreensSauerkraut (Wild Brine, Bubbles brands, etc)
CarrotsOnion, Garlic, LeeksPickles
ParsnipsJicamaKombucha
RadishesAsparagusApple Cider Vinegar
RutabagasUnderripe BananasKimchi
Sweet Potatoes, YamsChicory RootTempeh
BeetsAcacia GumMiso

When we take care of our Microbiome, it takes care of us

Our Most Dangerous Food

How Linoleic acid (Omega 6) fats WRECK our health– worse than sugar!

Our diets have changed greatly in comparison to our ancestors.

Then: In 1850: We ate 2-3 grams per day of linoleic acid (from seed oils).   Linolenic Acid use to make up 1% – 3% of the energy in the human diet and there was virtually no cancer, heart disease, obesity, diabetes, macular degeneration

Now: We on average eat 30 – 40 grams  of linolenic acid. This makes up 15% – 20% of energy in our diet and we now have exploding rates of cancer, heart disease, obesity, diabetes, macular degeneration from increase of pervasive linoleic acid (LA) – perhaps the greatest health experiment in history!

Linoleic acid (LA) acts as a metabolic poisondamages our mitochondria

  • Primary contributor to nearly all chronic disease
  • Highly susceptible to oxidation including OXLAMS (oxidated LA metabolites)
  • Omega 3 to Omega 6 ratio is important
    • Can’t fix by just increasing Omega 3 fish oil intake – must decrease linoleic acid

Linoleic Acid is our Enemy – many feel better in just days by eliminating Linoleic acid

Factory-farmed Chicken fed LA rich grains (soybeans, corn) as well as the oils below:


https://www.news-medical.net/health/Oils-Rich-in-Linoleic-Acid.aspx

Healthy Saturated Fat is our Friend!

  • Beef is great – grass fed best
  • Antibiotic free pork
  • Organic or free-range chicken is fine.   Factory farmed chicken is not.
  • Ghee (clarified butter – best for those who are dairy sensitive) or grass fed butter
  • Tallow – saturated fat from beef (get grass fed or organic)
  • Lard – saturated fat from pork (get antibiotic-free, free range)
  • Avocados best or avocado oil
  • Coconut or coconut oil
  • Olives or Olive oil – Extra Virgin Olive Oil (EVOO) only, avoid the cheap stuff that is adulterated with cheap vegetable oils high in linoleic acid
  • Cocoa Butter
  • Palm Oil
  • Macadamia Oil

Note: Can be ordered online at fatworksfoods.com 

Cardiolipin is a particular fat ONLY located in our mitochondria.

  • 20% of all our fat is as Cardiolipin
    • Made up of 4 fatty acids
    • Can include LA, or EPA, or DHA,  oleic acid, palmitic acid etc.
  • LA in Cardiolipin is especially susceptible to oxidation
  • Animals typically develop cancer when LA in diet reaches 4% to 10% of energy intake since OXLAMs trigger cancer

High LA diets cause obesity, heart disease and High saturated fat diets don’t get fat or sick

High LA increases risk of Sunburn and raises risk of acute respiratory disease and Covid-19

Top Sources of LA:   May feel better in days

  • Chips fried in vegetable oil
  • Commercial salad dressings
  • French Fries and other fried foods
  • Virtually all processed foods

To learn more: https://articles.mercola.com/sites/articles/archive/2020/12/13/linoleic-acid-health-effects.aspx?ui=9e9a02979a17667dbd9b7e20d7c0daa8e9b7fa45f6d1d9734470678d22aa9b73&cid_source=dnl&cid_medium=email&cid_content=art1HL&cid=20201213_HL2&mid=DM746090&rid=1033683774